Between 1945 and 1949 Janet Watson, a hematologist in Brooklyn, noticed that sickling of cells began ONLY after fetal hemoglobin in the young infant was replaced by the slightly altered variety, adult hemoglobin. This natural process, a transition that happens in each one of us, was her clue that the real culprit was adult hemoglobin. In this case, the only difference is the hemoglobin itself.But how to prove it?
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