Consider this chart of engineered large-scale structures and their molecular counterparts. This may give you an idea of the molecular shapes that allow molecules to work in their dynamic 3-D world.
Technology | Function | Molecular example(s) |
Struts, beams, crosslinks * | Transmit
force Reinforce |
Microtubules, cellulose, mineral casings |
Cables | Transmit tension | Collagen |
Gears* * | Conformation-changing protein actuators, moving things | Actin and myosin; see molecular gear |
Motors | Turn shafts | Flagellar motor |
Containers, packaging | Hold fluids, ingredients for catalysis | Lipid vesicles |
Pipes | Carry fluids | Various tubular structures |
Pumps | Move fluids and ions | Membrane proteins that pump ions and molecules |
Conveyor belts | Move components | RNA moved by fixed ribosome (partial analog) |
Clamps | Hold workpieces | Enzymatic binding sites |
Hinges | Join units flexibly* | Enzymatic binding sites |
Measure | Determine size | Enzymatic function |
Cutters | Cut into pieces |
Enzymatic role e.g., Lysosyme |
Bearings | Smooth motion | molecular bearings. |
Source: Adapted from K. Eric Drexler , Molecular engineering:An approach to the development of general capabilities for molecular manipulationProceedings of the National Academy of Sciences, USA. Vol. 78, No. 9, pp. 5275-5278, September 1981 [ PERMISSION PENDING] See http://www.imm.org/PNAS.html
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