Consider this chart of engineered large-scale structures and their molecular counterparts. This may give you an idea of the molecular shapes that allow molecules to work in their dynamic 3-D world.

Technology  Function  Molecular example(s)
 Struts, beams, crosslinks *  Transmit force
Reinforce
Microtubules, cellulose, mineral casings
 Cables  Transmit tension  Collagen
Gears* *  Conformation-changing protein actuators, moving things  Actin and myosin; see molecular gear
 Motors  Turn shafts  Flagellar motor
 Containers, packaging  Hold fluids, ingredients for catalysis Lipid vesicles
 Pipes  Carry fluids  Various tubular structures
 Pumps  Move fluids and ions  Membrane proteins that pump ions and molecules
 Conveyor belts Move components  RNA moved by fixed ribosome
(partial analog)
 Clamps  Hold workpieces  Enzymatic binding sites
Hinges  Join units flexibly* Enzymatic binding sites
Measure  Determine size  Enzymatic function
 Cutters  Cut into pieces

 Enzymatic role

e.g., Lysosyme

 Bearings  Smooth motion  molecular bearings.


Source: Adapted from K. Eric Drexler , Molecular engineering:An approach to the development of general capabilities for molecular manipulationProceedings of the National Academy of Sciences, USA. Vol. 78, No. 9, pp. 5275-5278, September 1981 [ PERMISSION PENDING] See http://www.imm.org/PNAS.html

Go On to explore molecules.



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